The results of Pueraria mirifica extract, diadzein and genistein in testosterone-induced prostate hyperplasia in male Sprague Dawley rats. Keywords: Benign prostatic hyperplasia; Pueraria mirifica; daidzein; genistein. The evaluation of histoarchitechture of the prostate has also shown that there was a significant enchancment in prostatic cells of the testosterone-induced rats when handled with PM extract, daidzein and genistein. This was confirmed by prostate-specific antigen stage that considerably decreased when handled with PM extract, daidzein and genistein. Testosterone was administered at 3 mg kg(-1) to rats followed by the PM extract, daidzein and genistein for a period of 30 days with finasteride as constructive control. The PM extract, daidzein and genistein lowered the rise in the prostate/physique weight ratio in testosterone-induced rats. This provides indication that PM extract, daidzein and genistein possessed protecting exercise for the therapy of benign prostatic hyperplasia. Cynanchum wilfordii Ameliorates Testosterone-Induced Benign Prostatic Hyperplasia by Regulating 5α-Reductase and Androgen Receptor Activities in a Rat Mannequin.
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